Contributing factors include the availability of iron tablets and their candylike appearance. Haddad and Winchester's clinical management of poisoning and drug overdose (Fourth ed.). Iron poisoning is a common toxicologic emergency in young children. Goldfrank's toxicologic emergencies (Tenth ed.). Quebec, Canada: Centre antipoison du Quebec.īalmadrid, C., & Bono, M. Antidotes en toxicologie d'urgence (3rd ed.). Prompt treatment in the hospital can be life-saving. Any overdose of iron-containing products should be taken seriously. Serial ophthalmological and audiological testing should be performed, if symptoms noted and then as necessary.īailey, B., Blais, R., Gaudreault, P., Gosselin, S., & Laliberte, M. (2009). Iron toxicity can eventually lead to seizures, coma, multiple organ failure, and death. Visual disturbances, hearing loss and audiometric abnormalities have been reported, especially if high doses used. PDF Iron is a substance commonly found in the homes of many children, leading to a high potential for accidental ingestion.Infection with yersinia species or mucormycosis may be promoted by deferoxamine.Decreased serum glucose, sodium, calcium and increased blood coagulability.Rapid IV injection (greater than 15 mg/kg/hour) has produced flushing, urticaria, hypotension and shock.Treatment should be interrupted if signs of toxicity occur. Respiratory distress syndrome has been reported following IV administration of excessive doses. Allergic reactions (dermatological, anaphylaxis).Reddish discolouration of the urine as chelated iron is being excreted.Pain and induration at the site of injection.Headache, nausea, urticaria, arthralgia, myalgia, fever.Infusions greater than 24 hours may be associated with severe or fatal pulmonary toxicity.
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